The Paragon staining solution for mineralized hard tissue has been specially developed for the histological examination of bones and teeth. It is used in fields such as histopathology, dentistry and osteology to visualize structures and pathologies in mineralized tissues.

The chemical mode of operation is based on the interaction of the dyes toluidine blue and basic fuchsin with the tissue components. Toluidine blue binds to acidic molecules, such as proteoglycans, and stains them blue, while basic fuchsin attaches to basic components, such as collagen fibers, and stains them red. This creates a contrast that facilitates differentiation between various tissue components.

The special suitability of Paragon staining solution lies in its ability to selectively stain various structures in mineralized hard tissues, facilitating the examination and identification of structures and possible pathologies. The combination of toluidine blue and basic fuchsin in an aqueous-alcoholic solution ensures efficient staining of tissue samples and enables detailed morphological assessments.