EDTA Decalcifying Solution ~ 10 %
EDTA decalcification solution with about 10% concentration is mainly used in histology and pathology to prepare bone and calcified tissue specimens for microscopic examination. EDTA (ethylenediaminetetraacetic acid) is a chelating agent that selectively removes calcium ions from tissue to dissolve calcifications.
This EDTA solution is prepared by dissolving EDTA in water and then adjusting it to a pH of approximately 7.4. The solution allows for gentle decalcification of tissue specimens by extracting calcium ions from the tissue without affecting the morphological and cellular structures.
The 10% EDTA decalcification solution is usually applied to the specimen for an extended period of time, and the process can take several days to weeks depending on the size and density of the specimen. The solution should be changed regularly to ensure efficient decalcification.
The EDTA decalcification solution is specifically designed for professional use in histology and pathology laboratories, providing an effective and gentle method for preparing bone and calcified tissue specimens for microscopic examination. The solution is also suitable for decalcification of samples to be prepared for immunohistochemistry or in situ hybridization, as it largely preserves antigenicity and nucleic acids.
This EDTA solution is prepared by dissolving EDTA in water and then adjusting it to a pH of approximately 7.4. The solution allows for gentle decalcification of tissue specimens by extracting calcium ions from the tissue without affecting the morphological and cellular structures.
The 10% EDTA decalcification solution is usually applied to the specimen for an extended period of time, and the process can take several days to weeks depending on the size and density of the specimen. The solution should be changed regularly to ensure efficient decalcification.
The EDTA decalcification solution is specifically designed for professional use in histology and pathology laboratories, providing an effective and gentle method for preparing bone and calcified tissue specimens for microscopic examination. The solution is also suitable for decalcification of samples to be prepared for immunohistochemistry or in situ hybridization, as it largely preserves antigenicity and nucleic acids.
Article no.: 12584
Decalcification of tissue samples
product information
Relevant Incredients:
• EDTA
• TRIS