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Testing Solution for Osmotic Resistance of Erythrocytes

The test solution for the osmotic resistance of erythrocytes serves as an important tool for medical and histological diagnostics. It measures the resistance of erythrocytes to hemolysis when exposed to a dilute saline solution. This results in the uptake of water by the cells, causing swelling and cell lysis. The solution is excellent for diagnosing conditions such as hereditary spherocytosis, thalassemia, iron deficiency anemia and sickle cell disease, as well as in cases of severe burns and poisoning.

The contained substance, BIS-TRIS, acts as a buffer and stabilizes the system despite variable conditions. Glycerol is also an important component, but its specific function in this solution could not be conclusively clarified despite research. This requires further investigation. The remaining components of the solution, including sodium chloride, sodium azide, and hydrochloric acid, also contribute to the overall effectiveness of the solution.

The use of the test solution may produce different results depending on the osmotic fragility of the erythrocytes. Increased osmotic fragility may be seen in cases of hereditary spherocytosis and hypernatremia, while decreased osmotic fragility may be seen in chronic liver disease, iron deficiency anemia, thalassemia, and other conditions.

Article no.: 15162

Osmotic resistance test

Important Information

Warning labels:

Lagerung: 4 … 8 °C

Haltbarkeit: 24 Monate

product information

Relevant Incredients:

• Sodium chloride
• Sodium azide
• Glycerol
• Hydrochloric Acid 37%

Technical informations

specifications

Hazard and safety instructions

Signal Word 1: Achtung
Signal Word 2: exclam, , ,
Warning labels: