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Formaline-free Zinc Fixative (for IHC)

Formalin-free Zinc Fixative (for IHC) serves as a fixative solution in immunohistochemistry, where the absence of formalin reduces potential health risks and the need for special handling protocols.

The particular suitability of this fixative lies in its ability to preserve tissue quality and antigenicity, making it an attractive option for applications requiring high morphological and molecular preservation. Due to its composition, particularly the zinc chloride and zinc acetate, it creates a fixative solution that provides excellent tissue preservation.

The chemical function of this fixative is based on the interaction of zinc ions with protein structures in the tissue, resulting in fixation of the tissue structure. The zinc salts it contains, zinc acetate and zinc chloride, act synergistically, while calcium acetate and TRIS optimize the pH.

The operation of this formalin-free zinc fixative is similar to that of formaldehyde fixatives, with the advantage that it is less toxic and has fewer negative side effects. Fixation without formalin better preserves antigens in cells, which can lead to higher specificity and sensitivity in subsequent antibody detection. Overall, this fixative is ideally suited for use in a variety of diagnostic and scientific applications where antigen preservation and high fixation quality are essential.

Article no.: 14064

Fixation of tissue samples

  •   Container size and order number Net price Amount
    Formaline-free Zinc Fixative (for IHC) - 100 ml
    Order number: 14064.00100
    24,98 €
    Formaline-free Zinc Fixative (for IHC) - 250 ml
    Order number: 14064.00250
    26,98 €
    Formaline-free Zinc Fixative (for IHC) - 500 ml
    Order number: 14064.00500
    27,47 €
    Formaline-free Zinc Fixative (for IHC) - 1.000 ml
    Order number: 14064.01000
    48,29 €
    Formaline-free Zinc Fixative (for IHC) - 2.500 ml
    Order number: 14064.02500
    89,75 €

Important Information

UN-Nummer: 0000

Lagerung: 15 … 25 °C

Haltbarkeit: 3 Monate

safety data sheet


product information

Relevant Incredients:
• Calcium acetate
• acetic acid ; zinc (II)-compound
• Zinc chloride
• TRIS
• Hydrochloric Acid 1.0 mol/l

Technical informations

specifications

Instructions / Protocol / Recommendations

Verwendung:

Bei der Fixierung werden alle in der Zelle ablaufenden Prozesse unterbrochen, unter möglichst optimaler Erhaltung des Zustandes und der Struktur des Gewebes. Biochemische Prozesse wie Autolyse, Verwesung und Fäulnis werden wirkungsvoll verhindert. Fixierlösung nach Stieve eignet sich zur Fixierung von Hodengewebe und Eierstockgewebe. Die Fixierlösung ist ausschließlich für die professionelle Anwendung als in-vitro Diagnostikum im histologischen Labor vorgesehen.

Hazard and safety instructions