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Staining Kit: Silver Method after CAMPBELL-SWITZER

The Staining Kit: Campbell-Switzer Silver Plating is used as an essential in vitro diagnostic tool in neuropathology. By combining ammonia, citric acid, acetate buffer, sodium thiosulfate, silver pyridine carbonate and specific developer solution, it enables the visualization of Alzheimer's disease-specific pathological changes. It is designed for selective silver staining of amyloid plaques and neurofibrillary bundles. The chemical complexity of this kit leads to the formation of a reducing environment that converts silver ions into elemental silver. This attaches to the pathological structures and allows their visualization under the microscope. Successful application of this kit can lead to precise and detailed imaging results that can make a significant contribution to the diagnosis and understanding of neurodegenerative diseases such as Alzheimer's disease.

Article no.: 16854

Neurofibril staining

  •   Container size and order number Net price Amount
    Staining Kit: Silver Method after CAMPBELL-SWITZER - 100 ml
    Order number: 16854.00100
    78,31 €
    Staining Kit: Silver Method after CAMPBELL-SWITZER - 250 ml
    Order number: 16854.00250
    88,71 €
    Staining Kit: Silver Method after CAMPBELL-SWITZER - 500 ml
    Order number: 16854.00500
    175,34 €
    Staining Kit: Silver Method after CAMPBELL-SWITZER - 1.000 ml
    Order number: 16854.01000
    336,42 €

Important Information

UN-Nummer: siehe Einzelprodukte

Warning labels:

Lagerung: siehe Einzelprodukte


product information

Components of this kit:
• Horn softener for histology, Artikel-Nr.:14835
• Citric Acid 1 %, Artikel-Nr.:16827
• Acetate buffer pH 4.99 (stock solution), Artikel-Nr.:16859
• Sodium Thiosulfate 1 %, Artikel-Nr.:11155
• Kit: Silver Pyridine Carbonate acc. to CAMPBELL-SWITZER, Artikel-Nr.:16898
• Developing Solution for CAMPBELL-SWITZER Staining, Artikel-Nr.:16903

colouring protocol

Technical informations

specifications

Instructions / Protocol / Recommendations

Verwendung:

The staining kit: silvering according to CAMPBELL-SWITZER is a solution used especially for in vitro diagnostics of neurological diseases. This solution is mainly used in the staining of neurofibrils, which are relevant in the study of Alzheimer pathologies. By using this staining kit, neurofibrils can be visualized in cellular structures and tissue samples, allowing successful differentiation and analysis of healthy and pathologically altered tissue. This supports research into these diseases and helps in the development of diagnostic and therapeutic approaches.

Prinzip:

Campbell-Switzer silver plating is a staining method used in in vitro diagnostics for visualization and identification of tissue or cell structures, especially in the study of Alzheimer's pathologies. The principle of operation is based on the attachment of silver ions contained in the silver pyridine carbonate solution to specific structures in the tissue, such as amyloid plaques and neurofibrillary bundles. The binding of the silver ions to these structures allows their visualization under the microscope. The other solutions, such as ammonia, citric acid, acetate buffer, and sodium thiosulfate, are used to stabilize, activate, and reduce the silver ions in the tissue. The developer solution enhances the staining to make the structures more visible. Overall, this technology enables improved analysis of Alzheimer's-associated changes in brain tissue.

Verfahren:

Campbell-Switzer silver plating is a staining method used in in vitro diagnostics for visualization and identification of tissue or cell structures, especially in the study of Alzheimer's pathologies. The principle of operation is based on the attachment of silver ions contained in the silver pyridine carbonate solution to specific structures in the tissue, such as amyloid plaques and neurofibrillary bundles. The binding of the silver ions to these structures allows their visualization under the microscope. The other solutions, such as ammonia, citric acid, acetate buffer, and sodium thiosulfate, are used to stabilize, activate, and reduce the silver ions in the tissue. The developer solution enhances the staining to make the structures more visible. Overall, this technology enables improved analysis of Alzheimer's-associated changes in brain tissue.

Hazard and safety instructions

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Signal Word 2: acid_red, Aquatic-pollut-red, exclam, silhouete
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