Alum Carmine for Nuclear Staining
Alaunkarmine for nuclear staining is an important component in the field of histological examinations. Its main application is in the selective staining of cell nuclei, highlighting its particular suitability for visualizing cell nuclei in biological specimens.
Carmine, also known as cochineal, is a natural dye obtained from the cochineal scale insect (Dactylopius coccus). This insect species lives on certain species of cacti in Central and South America, where it has been used for centuries for dye extraction.
Chemically, carmine is an aluminum complex of carminic acid, an anthraquinone-like compound. Carminic acid is the main component of the dye and is responsible for its intense red color. Its chemical structure contains several functional groups, including hydroxyl groups and a carboxyl group, which are capable of binding to nucleic acids. The bond between the carminic acid and the nucleic acids is strong enough to ensure a permanent and stable coloration. The aluminum complex formed by the pickling action of alum further improves the binding properties and stability of the dye.
The chemical properties of alum carmine are further improved by the addition of formaldehyde and potassium alum. Formaldehyde acts as a fixative, while potash alum acts as a mordant and enhances the binding properties of the dye. When combined with water, this mixture forms a ready-to-use solution that enables accurate and differentiated visualization of cell structures.
The functionality of alum amine for nuclear staining is based on its ability to bind selectively to nucleic acids. This enables detailed visualization of cell nuclei, which is of great benefit in medical diagnostics and life sciences.
Carmine, also known as cochineal, is a natural dye obtained from the cochineal scale insect (Dactylopius coccus). This insect species lives on certain species of cacti in Central and South America, where it has been used for centuries for dye extraction.
Chemically, carmine is an aluminum complex of carminic acid, an anthraquinone-like compound. Carminic acid is the main component of the dye and is responsible for its intense red color. Its chemical structure contains several functional groups, including hydroxyl groups and a carboxyl group, which are capable of binding to nucleic acids. The bond between the carminic acid and the nucleic acids is strong enough to ensure a permanent and stable coloration. The aluminum complex formed by the pickling action of alum further improves the binding properties and stability of the dye.
The chemical properties of alum carmine are further improved by the addition of formaldehyde and potassium alum. Formaldehyde acts as a fixative, while potash alum acts as a mordant and enhances the binding properties of the dye. When combined with water, this mixture forms a ready-to-use solution that enables accurate and differentiated visualization of cell structures.
The functionality of alum amine for nuclear staining is based on its ability to bind selectively to nucleic acids. This enables detailed visualization of cell nuclei, which is of great benefit in medical diagnostics and life sciences.
Article no.: 10123
Cell nuclei staining
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Lagerung: 15 … 25 °C
Haltbarkeit: 12 Monate
product information
Relevant Incredients:
• Potassium alum
• Carmine (C.I.: 75470)
• Formaldehyde ~37%, stabilised
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